Five models. Four domains. One announcement.
On March 16, NVIDIA released Nemotron 3, Isaac GR00T N1.7, Alpamayo 1.5, Cosmos 3, and Proteina-Complexa, five open model families spanning agentic AI, humanoid robotics, autonomous vehicles, and protein drug discovery. According to NVIDIA’s official announcement, the releases are designed to advance what the company calls the “next wave of agentic AI.”
Nemotron 3 is the agentic centerpiece. NVIDIA states it supports natural conversation, complex reasoning, and multi-agent task completion. Nemotron 3 Super is available now, with developer cookbooks included. According to NVIDIA’s developer blog, Nemotron 3 Super delivers up to 5x higher throughput, though the baseline for that comparison isn’t specified in available materials, and no independent evaluation has confirmed the figure.
The physical AI releases are distinct. Isaac GR00T N1.7 is a reasoning vision language action (VLA) model for humanoid robots. Alpamayo 1.5 applies the same VLA architecture to autonomous vehicles. Cosmos 3 is a world foundation model for synthetic environment generation, a simulation layer that physical AI systems can train against.
On the science side, Proteina-Complexa, part of NVIDIA’s BioNeMo platform, targets protein drug discovery. Its release came with an open dataset of AI-predicted protein complex structures. EMBL’s European Bioinformatics Institute confirmed its participation in the dataset release. According to NVIDIA, Google DeepMind and Seoul National University also contributed, though that involvement is confirmed only through NVIDIA-sourced materials.
No independent benchmark evaluation is available for any of these models. Epoch AI review is pending.