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Microsoft has patched two actively exploited zero-day vulnerabilities in its Defender security product line, affecting the Malware Protection Engine and Antimalware Platform deployed across Windows enterprise environments. CVE-2026-41091 allows attackers to gain full administrative control (SYSTEM privilege, equivalent to operating system-level access) of affected endpoints; CVE-2026-45498 can disable endpoint protection at scale, leaving systems undetected and undefended. CISA has added both to the Known Exploited Vulnerabilities catalog with a June 3, 2026 remediation deadline for federal agencies, and the broad deployment of Defender across enterprise Windows fleets makes rapid verification of patch delivery a priority for all organizations.

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